TITLE:
Male Breast Cancer: A Three-Patient Case Series of Clinico-Pathological Features and Therapeutic Challenges
AUTHORS:
Alhassane I. Touré, Mamady Keita, Mihimit Abdoulaye, Abdoulaye M. Camara, Malick Bah, Kalil Cisse, Ibrahima Kalil Condé, Mohamed F. Cisse, Boubacar 1 Barry, Ousmane Koulibaly, Mamadou C. F. Diallo, Abou Camara, Arbaba Balde, Bangaly Traoré
KEYWORDS:
Male Breast Cancer, Invasive Ductal Carcinoma, Papillary Carcinoma, Case Series, Donka, Guinea
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.17 No.11,
November
5,
2026
ABSTRACT: Introduction: Breast cancer in men is a rare condition, accounting for approximately 1 per cent of all breast cancers and less than 0.9 per cent of cancers in men. Owing to its rarity and low public awareness, the diagnosis is often made at a late stage. Furthermore, treatment recommendations are based primarily on data from female breast cancer, in the absence of specific studies in men. Objective: To describe the clinical, pathological and therapeutic characteristics of three cases of male breast cancer managed in our oncology department. Methods: We conducted a retrospective study involving three male’s patients with breast cancer. Demographic, clinical, radiological, pathological and therapeutic data were collected from medical records and subsequently analysed. Results: The patients were aged between 34 and 60 years and presented with a variety of clinical presentations, ranging from a painless breast nodule to a locally advanced ulcerated and exudative mass. Pathological examination revealed two invasive ductal carcinomas and one papillary carcinoma. Management, tailored to the stage of the disease, was based on a multidisciplinary approach combining surgery, radiotherapy, chemotherapy and hormone therapy if indicated. Conclusion: Although rare, breast cancer in men presents a real diagnostic and therapeutic challenge. Greater awareness amongst healthcare professionals and the general public, as well as the development of specific studies, are essential to promote earlier diagnosis and improve the management of this condition.