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Lupande, D., Kaishusha, D., Mihigo, C., Itongwa, M., Yenga, G. and Katchunga, P. (2017) GeneXpert MTB/RIF dans le dépistage de la tuberculose pulmonaire à l’Hôpital Provincial Général de Référence de Bukavu, à l’Est de la République Démocratique du Congo: Quelles leçons tirées après 10 mois d’utilisation? Pan African Medical Journal, 27, Article 260.
https://doi.org/10.11604/pamj.2017.27.260.12575

has been cited by the following article:

• TITLE: Molecular Profile of Rifampicin and Isoniazid Resistance in the Mycobacterium tuberculosis Complex at Paul VI Hospital in Ouagadougou: A Study Based on GeneXpert MTB/RIF Ultra and MTB/XDR Tests

  AUTHORS: Désiré Ilboudo, Koudpoko Madeleine Kabre, Herman Karim Sombie, Pegdwendé Abel Sorgho, Prosper Bado, Albert Théophane Yonli, Adjima Combary, Bapio Valérie Jean Télesphore Elvira Bazie, Harouna Kiendrebeogo, Théodora Mahoukèdè Zohoncon, Yacoubou Bakasso, Jacques Simpore

  KEYWORDS: Tuberculosis, Molecular Resistance, Rifampin, Isoniazid, Burkina Faso

  JOURNAL NAME: American Journal of Molecular Biology, Vol.16 No.4, October 30, 2026

  ABSTRACT: Introduction: Tuberculosis (TB) remains a major public health problem, particularly in Burkina Faso. The emergence of strains resistant to rifampin (RIF) and isoniazid (INH) compromises the effectiveness of standard treatments. This study aimed to describe the molecular profile of rifampicin and isoniazid resistance in Mycobacterium tuberculosis complex among patients treated at Paul VI Hospital in Ouagadougou, based on results obtained from the Xpert MTB/RIF Ultra and Xpert MTB/XDR tests. Methods: This was a descriptive cross-sectional study conducted from January 2023 to December 2024. Sputum samples were analyzed by microscopy and by GeneXpert MTB/RIF and MTB/XDR to detect the Mycobacterium tuberculosis complex and resistance mutations. Results: Of the 4,358 patients included, the mean age was 40.80 ± 17.73 years, with a significant predominance of males (66.82%; male-to-female ratio = 2; p