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Rho, N.K. and Gil, Y.C. (2021) Botulinum Neurotoxin Type a in the Treatment of Facial Seborrhea and Acne: Evidence and a Proposed Mechanism. Toxins, 13, Article 817.
https://doi.org/10.3390/toxins13110817

has been cited by the following article:

• TITLE: Prospective Evaluation of Intradermal Botulinum Toxin Type A Microinjections for Sebum Reduction and Acne Improvement in Adults: A Single-Centre Interventional Study

  AUTHORS: Maryna Spivak

  KEYWORDS: Botulinum Toxin Type A, Intradermal Microinjections, Acne Vulgaris, Seborrhoea, Sebum Reduction, Microtoxin, Aesthetic Dermatology

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.14 No.11, October 30, 2026

  ABSTRACT: Sebum overproduction is a key factor in acne vulgaris and seborrhea. This prospective, single-center, interventional study evaluated the efficacy and safety of standardized intradermal microinjections of botulinum toxin type A (BoNT-A) in 42 adults with mild-to-moderate facial acne and seborrhea. Participants received 40 - 60 units of onabotulinumtoxin A via microdroplet technique. Outcomes included sebum levels (Sebumeter), acne lesion counts, patient satisfaction (Visual Analogue Scale [VAS] and Global Aesthetic Improvement Scale [GAIS]), and adverse events. After treatment, sebum production was observed to decrease by 47.9% at 4 weeks and 35.2% at 12 weeks (p