TITLE:
Phyllodes Breast Sarcomas: A Report on 5 Cases and Review of Literature
AUTHORS:
Aissatou Mbodji, Moussa Diallo, Daba Diop, Diomaye Sene, Babacar Biaye, Mouhamadou Wade, Mamour Gueye
KEYWORDS:
Phyllodes Sarcoma, Breast, Oncology, Surgery
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.17 No.10,
October
21,
2026
ABSTRACT: The objective of this study was to examine the clinical characteristics and management of five patients with phyllodes sarcoma of the breast. These patients were followed at the senology unit of the Philippe Maguilen Senghor health center in Dakar between 2012 and 2022. We conducted a retrospective study of five cases of phyllodes sarcoma managed at our unit. We collected clinical, histopathological, and therapeutic data from the patients’ medical records. We also followed the patients’ outcomes, including recurrence and survival, for up to 36 months after treatment. The mean age of the five patients at diagnosis was 28.8 years. Mastectomy was the primary treatment most of the patients. Two patients developed local recurrences within a very short time, between 4 and 20 months. The overall survival rate for the five patients was 40% at 24 months. Phyllodes sarcomas of the breast are rare tumors that require special attention due to their potential for progression. Early diagnosis and adequate surgical resection are crucial to reduce the risk of recurrence. This case report highlights the challenges of managing these tumors and emphasizes the importance of rigorous follow-up.