TITLE:
Amoebic Liver Abscess in a Hospital Setting in Bamako, Mali
AUTHORS:
Abdoulaye Mamadou Traore, Ibrahim Dollo, Mohamed Ibrahim Traore, Hamsatou Cisse, Djibril Sy, Tidiani Cisse, Douro Ouologuem, Brahima Sall-Bah, Kaly Keita, Aminata Maiga, Menta Djénébou Traore, Amagana Dolo, Assetou Soukho Kaya, Moussa Tiemeko Diarra, Zimogo Zié Sanogo, Hamar Alassane Traore, Daouda Kassoum Minta
KEYWORDS:
Amoebic Abscess, Ultrasound, Serology, Hepatomegaly
JOURNAL NAME:
Advances in Microbiology,
Vol.16 No.10,
October
16,
2026
ABSTRACT: Through a descriptive study with retrospective data collection, the authors described the current epidemiological, clinical, paraclinical, and therapeutic characteristics of amoebic liver abscess in a hospital setting in Bamako. Over a 16-year period, 35 cases were recorded, 17 of which had secondary infections. Bacterial superinfection occurred in 12 HIV-infected patients and 5 non-HIV cases. The sex ratio (M/F) was 2.88. The main physical signs noted were tenderness on percussion (100%), hepatomegaly (94.28%), fever (82.85%), conjunctival pallor (37.14%), jaundice (34.28%), and right-sided pleural effusion syndrome (28.57%). The pleural fluid infected was most often chocolate-colored (70%). HIV serology was positive in 34.28% of cases. Amoebic serology was positive in 100% of cases. Liver ultrasound revealed hepatomegaly with a single abscess (68.57%) or multiple abscesses (31.42%), particularly in HIV-positive patients. The combination of a nitroimidazole and other bactericidal antibiotics successfully treated 12 cases with secondary bacterial infections (34.28%). The in-hospital mortality rate was 5.71%.