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Shuai, X.X., Chen, Y.Y., Lu, Y.X., Su, G.H., Wang, Y.H., Zhao, H.L. and Han, J. (2011) Diagnosis of heart failure with preserved ejection fraction: Which parameters and diagnostic strategies are more valuable? The European Journal of Heart Failure, 13, 737-745.

has been cited by the following article:

• TITLE: How many systolic and diastolic variables must be measured in elderly patients with symptoms of heart failure?

  AUTHORS: Jan B. Remmets, Mona K. Olofsson, Hans Stenlund, Kurt O. Boman

  KEYWORDS: Echocardiography; Systole; Diastole; Elderly; Primary Health Care

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.2 No.2, April 25, 2012

  ABSTRACT: Objectives: To explore the concordance and the feasibility of obtaining systolic or diastolic variables of left ventricular function in elderly patients with heart failure symptoms. Methods: One hundred twenty four patients with symptoms of heart failure (mean age 77 years, 70% females) were included in a cross-sectional, explorative study. Nineteen echocardiographic variables (7 systolic and 12 diastolic) were measured. Results: Overall, feasibility ranged from 93% to 100% for 15 variables and was 48% for mitral regurgitation dp/dt(MRdp/dt), 66% for the difference between pulmonary AR-dur and mitral A-dur, 81% for the ratio between early and late mitral inflow velocity (E/A), and 76% for tissue Doppler imaging late dia-stolic velocity (TDI A’). Concordance was very good/ good in 83% and poor/missing in 17% of systolic variables, whereas it was very good/good for 67% of diastolic variables and poor/missing for 33%. Factor analysis reduced systolic variables to two factors that explained 69% of the total variance in systolic function. Conclusions: Low feasibility for some and questionable concordance of especially diastolic variables questions the rationale for routinely measuring a high number of echocardigraphic variables. The results of the factor analysis further strengthen the possibility of reducing the number of measured variables. The clinical value of such a reduction needs to be validated.