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Hiromasa, S., Sachio, K., Tadanori, A., et al. (1999) Histological evaluation of coronary plaque in patients with variant angina: Relationship between vasospasm and neointimal hyperplasia in primary coronary lesions. Journal of the American College of Cardiology, 33, 198-205. doi:10.1016/S0735-1097(98)00520-8

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• TITLE: Rapid decrease of necrotic core after acute myocardial infarction

  AUTHORS: Jun Ho Lee, Eun-Seok Shin, Shin-Jae Kim, Jong Min Kim, Jung Won Hwang, Hector M. Garcia-Garcia, Patrick W. Serruys

  KEYWORDS: Vulnerable Plaque; IVUS; Acute Myocardial Infarction; Variant Angina

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.2 No.2, April 25, 2012

  ABSTRACT: It is well known that the increase of necrotic core in previous atherosclerotic coronary artery disease is one of the conditions of vulnerable plaque. However, it is not known how fast necrotic core could decrease in a vulnerable plaque. We had 2 patients who had suffered from acute myocardial infarction and had large amount of necrotic core in their culprit lesions at baseline, which decreased markedly within 7 days. Also, they were clinically stable and asymptomatic over 1 year follow-up. It is first report to show mar-kedly decrease of necrotic core amount within only 7 days in culprit lesions of 2 cases of acute myocardial infarction with angiographically minimal lesions.