TITLE:
Effect of Hospital-Wide Active Blood Glucose Management Model on Glycemic Control and Clinical Outcomes in Patients with Community-Acquired Pneumonia and Type 2 Diabetes Mellitus: A Retrospective Before-After Controlled Study
AUTHORS:
Shuhong Tan, Jingying Zhou, Nenghua Tang, Chongrong Long, Sheng Li, Yuting Yin, Xiaoxia Zou, Ying Wang, Linlin Tian, Qirui He, Ting Li, Qun Wu, Yingsha Li
KEYWORDS:
Active Blood Glucose Management throughout the Hospital Community-Acquired Pneumonia Type 2 Diabetes Blood Sugar Control Clinical Outcome
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.14 No.9,
September
29,
2026
ABSTRACT: Objective: This paper aims to evaluate the impact of the hospital-wide active blood glucose management model on blood glucose control, clinical outcomes and resource utilization in patients with community-acquired pneumonia (CAP) complicated with type 2 diabetes mellitus (T2DM). Method: In this single-center retrospective before-and-after controlled study, patients with CAP combined with T2DM were divided into the traditional consultation management group (n = 229) and the hospital-wide blood glucose management group (n = 218) based on the implementation time of the active management model. The baseline data, primary outcomes (blood glucose control indicators), and secondary outcomes (hard clinical endpoints and resource utilization indicators) of the two groups were compared. Spearman correlation analysis was used to explore the associations among variables. Result: There were no statistically significant differences in baseline variables (including age, duration of diabetes, HbA1c, WBC, CRP, PCT, PaO2, PaCO2 and PSI score) between the two groups (all P > 0.05). The rate of reaching the target blood glucose at discharge in the hospital-wide blood glucose management group was significantly higher (73.4% vs 61.6%, P = 0.010), the time to reach the target blood glucose was shorter (P = 0.017), the highest blood glucose was lower (P 0.05). Relevant analysis shows that the total hospitalization cost is positively correlated with the length of hospital stay and the length of stay in the ICU, the lowest blood glucose is positively correlated with the frequency of hypoglycemia, and there is an aggregated correlation among inflammatory markers. Conclusion: The hospital-wide active blood glucose management model can significantly improve the short-term blood glucose control of patients with CAP combined with T2DM without increasing the economic burden, but it has not translated into significant benefits of hard clinical endpoints. Multicenter prospective randomized controlled trials with extended follow-up periods are still needed to fully verify its long-term value.