TITLE:
Acute Coronary Syndromes in Black African Women at the “Le Luxembourg” Mother-Child University Hospital Center in Bamako: About 195 Cases
AUTHORS:
Mahamat Guire Sadik, Toure Mamadou, Sidibe Samba, Konate Massama, Sankare Hamma, Traore Ousmane, Diall Mahan Ameri, Dagnogo Mariam, Keita Asmaou, Coulibaly Souleyman, Menta Ichaka
KEYWORDS:
Acute Coronary Syndrome, Coronary Angiography, Women, Le Luxembourg Mother-Child University Hospital Center, Bamako
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.16 No.9,
September
20,
2026
ABSTRACT: Introduction: Worldwide, cardiovascular pathologies, particularly coronary heart disease, are the leading cause of death in women. In Mali and sub-Saharan Africa in general, few data exist on acute coronary syndromes (ACS) in women; hence the initiative for this study, whose main objective is to investigate the sociodemographic, clinical, paraclinical, therapeutic and evolutionary aspects of acute coronary syndrome in black women. Methodology: This is a descriptive, cross-sectional study with retrospective and prospective recruitment, concerning female patients admitted for acute coronary syndrome over a period of 4 years and 5 months from September 2019 to January 2024 within the interventional cardiology unit of the Mother-Child University Hospital Center in Bamako, Mali. Results: Of a total of 596 patients admitted for acute coronary syndrome during the period, 195 were female, representing a 32.72% hospitalization rate for ACS in women. The mean age of the patients was 59.82 ± 11.45 years [21 and 86 years], with the 45 - 65 age group the most affected. Risk factors were mainly hypertension 68.2% (n = 133), sedentary lifestyle 66.2% (n = 129), and diabetes 55.4% (n = 108). The predominant functional sign was typical chest pain in 65.1% of cases (n = 127). Clinical examination was normal in 76.92% (n = 150) of patients. Electrical findings were mainly persistent ST-segment elevation in 56.9% (n = 111). Seventy-eight percent (n = 153) of patients were managed 12 h after first medical contact. The approach for coronary angiography was radial in 93.33%. Coronary angiography was pathological in 76.4% (n = 149). The anterior interventricular artery was the most affected artery in 65.64% (n = 128) of cases. Lesions were significant in 93.29% (n = 139) and 82.55% (n = 123) of cases of sub-occlusions and occlusions. Angioplasty was performed in 45.64% of our patients (n = 89), and active stents were used in 100% of cases. Five deaths were recorded among the complications during percutaneous coronary procedures and during in-hospital evolution. Conclusion: Acute coronary syndrome is not uncommon in women in sub-Saharan Africa. Typical chest pain is the most frequent symptomatology. Delayed diagnosis and treatment remain a major problem.