TITLE:
Obstetrical Success of a Very High-Risk Pregnancy in a Patient with Severe Systemic Sclerosis and a History of Three Fetal Deaths and One Neonatal Death
AUTHORS:
Soukaina Daoudi, Richie Ifuta, Blaise Bonga, Milène Tshibola Nkashama, Nisrine Hsissi, Aicha Gotni, Asmaa Assal, Mohamed Mehdi Bensouda, Mohamed Jalal, Amine Lamrissi, Naima Samouh
KEYWORDS:
Systemic Sclerosis, High-Risk Pregnancy, Azathioprine, Interstitial Lung Disease, Intrauterine Fetal Death (IUFD)
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.16 No.9,
September
20,
2026
ABSTRACT: This case report describes the successful multidisciplinary management, within a specialized facility, of a very high-risk pregnancy in a 42-year-old patient with systemic sclerosis (SSc). The disease was stable under azathioprine (150 mg/day) and characterized by double immunological positivity (ANA, anti-centromere) along with severe dual involvement: mucocutaneous and interstitial lung disease (pure restrictive ventilatory defect with TLC