TITLE:
Microalbuminuria in Sickle Cell Patients at the Hematology-Oncology Department of Donka National Hospital
AUTHORS:
Kalil Nouny Sidibé, Mohamed Cissoko, Mamadou Diakhaby, Mohamed Lamine Conté, Maomy Jacques, Lanciné Kourouma, Aboubacar Dioubaté, Sâa Joseph Téliano, Mohamed Adama Oularé, Amara Magassouba, Kanté Mamadou Aliou II, Diallo Mamadou Tafsir, Idrissa Diallo, Abraham Geopogui, Oumar Camara, Abdourahmane Diallo, Elhadj Salmana Diallo, Amadou Baillo Barry, Fatoumata Bah, Djibril Sylla, Amadou Kaké
KEYWORDS:
Microalbuminuria, Sickle Cell Disease, Hematology-Oncology, Donka University Hospital
JOURNAL NAME:
Open Journal of Internal Medicine,
Vol.16 No.3,
September
16,
2026
ABSTRACT: Introduction: Sickle cell disease is the most common autosomal recessive genetic disorder affecting the beta chain of hemoglobin. The objective of this study was to determine the prevalence of microalbuminuria in individuals with sickle cell disease. Methods: This was a prospective descriptive study conducted over a 6-month period, from July 1st to December 31st, 2020. We included in this study all patients hospitalized in the hematology-oncology department who had undergone hemoglobin electrophoresis and in whom the diagnosis of Sickle cell disease was confirmed, and the patient had no history of conditions causing proteinuria, so microalbuminuria was investigated. Data analysis was performed using Epi Info 2008 version 7.1.1 software. Results: Of 40 patients admitted to the Hematology-Oncology department of Donka National Hospital, 15 had microalbuminuria, representing a frequency of 37.5%. The 20 - 29 age group was the most represented. Men were more affected than women, at 53% versus 47%. A serum protein concentration of 150 mg/L was the most common, occurring in 56% of homozygous SS sickle cell patients. Moderate anemia was the most frequent finding, with a prevalence of 47.5% in sickle cell patients. Conclusion: Microalbuminuria is a common finding in sickle cell patients. To reduce this frequency, regular monitoring of sickle cell disease is necessary.