Article citationsMore>>
Tiash, S., Saunders, J., Hart, C.J.S., Ryan, J.H., Riches, A.G. and Skinner-Adams, T.S. (2020) An Image-Based Pathogen Box Screen Identifies New Compounds with Anti-Giardia Activity and Highlights the Importance of Assay Choice in Phenotypic Drug Discovery. International Journal for Parasitology: Drugs and Drug Resistance, 12, 60-67.
https://doi.org/10.1016/j.ijpddr.2020.03.002
has been cited by the following article:
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TITLE:
Organic Reactions between Therapeutic Compounds and Pathogenic Microorganism Cellular Chemical Components
AUTHORS:
Topwe Milongwe Mwene-Mbeja
KEYWORDS:
Therapeutic Compounds, Reaction Mechanisms, Glycoproteins, Glucolipids, Phospholipids, Deoxyribonucleic Acid (DNA)
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.16 No.3,
September
9,
2026
ABSTRACT: The biological properties of therapeutic compounds to degrade pathogenic microorganisms have been explained from organic chemistry perspective. Precisely, this paper has properly shown the mode of action concerning acidic therapeutic compounds possessing hydroxyl or carboxylic groups including alkaloid therapeutic compounds bearing a nitrogen atom or an amine group. In other words, this conceptual research has disclosed detailed reaction mechanisms, which demonstrate how an adequate medicine can neutralize or degrade one of the essential microbial cellular chemical constituents, such as the deoxyribonucleic acid (DNA).