TITLE:
Infectious Embryofoetopathies: Situation Analysis at the Charles DE GAULLE Paediatric University Hospital in Ouagadougou (Burkina Faso)
AUTHORS:
Aissata Kabore/Ouedraogo, Geovannie Youmbi, Laure Togueyeni/Tamini, Barguissa Konate, Diarra YE/Ouattara
KEYWORDS:
Embryofetopathy, TORCH, Toxoplasmosis, Rubella, CMV
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.16 No.5,
September
7,
2026
ABSTRACT: Introduction: Infectious embryofetopathies are infections mainly caused by pathogens of the TORCH group, transmitted from the mother to the fetus during pregnancy and which can have an impact on the product of conception. They represent a major public health problem because of their impact on neonatal morbidity and mortality. Objective: To take stock of infectious embryofetopathies in children hospitalized at CHUP CDG between July 1, 2021 and June 30, 2024. Method: We conducted a retrospective, descriptive and analytical cross-sectional study that involved the records of children hospitalized for infectious embryofetopathies between July 1, 2021 and June 30, 2024. Results: We included in our study 80 children hospitalized for embryofetopathy with an IgG positivity rate of 1.5%. There were 86.25% of newborns; male sex represented 62.50%. 51.25% of mothers had performed syphilis serology during pregnancy but none of them had performed the other serologies of the TORCH group; 86.25% of children were born at term. The main signs and symptoms found on admission were respiratory distress in 36.25% of cases, fever and jaundice in 27.50% of cases each; 65% of children had a visible malformation and the main internal anomalies objectified by imaging were cardiac anomalies in 56.28% of cases. The mortality rate during our study was 31.25%. Also, our study shows an association between positivity for anti-rubella IgG and death, but it does not establish that rubella is the cause of the malformations or the adverse outcome. Conclusion: It is important to screen for infectious embryofetopathies during pregnancy with the aim of caring for mothers in order to limit the occurrence of these pathologies in the newborn.