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Dunger, A., Cunningham, J. M., Delaney, C. A., Lowe, J. E., Green, M.H.L., Bone, A. J. and Green, I. C. (1996) Tumor necrosis factor-α and interferone-γ inhibit insulin secretion and cause DNA damage in unweanted-rat islets. Diabetes , 45, 183-189.

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• TITLE: Effect of prolonged intake of iron enriched diet on testicular functions of experimental rats

  AUTHORS: Mohamed M. El-Seweidy, Mervat E. Asker, Sousou I. Ali, Hebatallah H. Atteia

  KEYWORDS: Iron Overload; Oxidative Stress; Inflammatory Response of Rat Testis

  JOURNAL NAME: Natural Science, Vol.2 No.6, June 30, 2010

  ABSTRACT: Iron deficiency anemia represents a common nutritional problem which affects many societies allover the world and iron fortified diet has been suggested as one of possible tools to combat and solve such problem. Present study was designed to illustrate the effect of dietary iron intake on certain biochemical markers dealing with oxidative stress, inflammatory response and cellular alterations of testicular tissues. Adult male rats which were fed on biscuits fortified with iron (0.3% ferrous sulfate) daily for 10 weeks (iron group) showed increased serum iron, ferritin, tumor necrosis factoralpha (TNF-α), nitric oxide (NO) and decreased Testosterone level (p