TITLE:
Hematological Profile of Malaria-Infected Patients from Bangui, Central African Republic: A Retrospective Study at a Diagnostic Medical Center
AUTHORS:
Mireille Cornelia Ingrid Denissio Morissi Nalingbo, Justin Zabou, Romaric Nzoumbou-Boko
KEYWORDS:
Malaria, Hematological Parameters, Bangui, Central African Republic
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.14 No.6,
June
12,
2026
ABSTRACT: Background: Hematological disorders are the most common complications that determine the prognosis of malaria. Here, we compered hematological profiles of malaria-infected patients and malaria-negative patients at the Medical Analysis Laboratory of the Institute Pasteur in Bangui, Central African Republic. Methods: We conducted a retrospective study using archived data from 2 January to 30 December 2019 that included sociodemographic, parasitological, and hematological parameters. Results: The study showed that, out of the 518 subjects included, 28% were positive by microscopy. We detected a shift in the at-risk age group from the under 5 years age group to the 5–14 years age group. Approximately 47.49% of the study population and 69.5% of the children under 5 years were anemic. The mean values of hemoglobin were significantly lower in the malaria patients than the malaria-negative patients respectively 10.37 d/dL and 12.88 d/dL (p p Conclusion: Study participants infected with malaria demonstrated vital changes in hematological parameters, with anemia and neutrophilic leukocytosis being the most important associations observed in a retrospective laboratory-based study. Hematological alterations associated with malaria infection may vary depending level of malaria endemicity, background hemoglobinopathy, demographic factors and malaria immunity.