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Ge, S., Wang, B., Wang, Z., He, J. and Ma, X. (2022) Common Multiple Primary Cancers Associated with Breast and Gynecologic Cancers and Their Risk Factors, Pathogenesis, Treatment and Prognosis: A Review. Frontiers in Oncology, 12, Article 840431.
https://doi.org/10.3389/fonc.2022.840431

has been cited by the following article:

• TITLE: Multiple Primary Malignant Tumour: Case Report and Review of the Literature

  AUTHORS: Ny Ony Andrianandrasana, Hariniony Fanantenana Rafanomezantsoa, Norosoa Randriamaroson, Nomeharisoa Rodrigue Emile Hasiniatsy, Florine Rafaramino

  KEYWORDS: Cancer, Endometrial, Colon, Breast, Multiple Primary Malignant Tumour

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.14 No.6, June 10, 2026

  ABSTRACT: Two or more histologically distinct malignancies in one individual are termed as multiple primary malignant tumours (MPMT). There are currently no universal protocols based on evidence; instead, management is empirical and dependent on the judgments made by interdisciplinary teams. The authors’ aim was to report one case of MPMT seen in Madagascar and discuss according to the literature review. This case concerns a 63-year-old menaopausal Malagasy woman, followed in 2009 for an unprecised stage of adenocarcinoma of the colon, treated by a surgery followed by an adjuvant chemotherapy. Follow-up was fine with complete remission. Fourteen years later, another cancer localised in the endometrium was diagnosed as a high grade adenocarcinoma treated by surgery followed by a radiotherapy, which was combined with an invasive breast carcinoma treated by neoadjuvant chemotherapy, mastectomy and lymph node dissection, local radiotherapy and hormonotherapy. Management of MPMT is multidisciplinary and tailored to the stage of each tumor, prioritizing tumors with a poor prognosis.