TITLE:
Application Effect of “Case Management + Closed-Loop Management” Dual Nursing Management Mode in Patients with Chronic Hepatitis B in Clinical Cure Period
AUTHORS:
Yuping Wei, Qingcui Wu, Liya Zhu, Pan Jiang, Hui Hu
KEYWORDS:
Chronic Hepatitis B, Clinical Cure Period, Case Management, Closed-Loop Management, Nursing Management
JOURNAL NAME:
Yangtze Medicine,
Vol.10 No.2,
June
5,
2026
ABSTRACT: Objective: To explore the dual nursing management mode of “case management + closed-loop management” in chronic hepatitis B (CHB) clinical cure period, and the application value in patients provides practical basis for optimizing clinical nursing management strategy. Method: 60 cases admitted to our hospital from June 2024 to June 2025 were selected. Clinical cure of CHB period patients was randomly divided into observation group and control group with 30 cases in each group. The control group implemented the conventional management mode, while the observation group applied the dual nursing management mode of “case management + closed-loop management” on the basis of the conventional management. Medication compliance, nursing satisfaction, laboratory indicators and quality of life were compared between the two groups. Results: After the intervention, the good rate of medication compliance (83.3%) and nursing satisfaction (86.7%) in the observation group were significantly higher than those in the control group (56.7%, 63.3%). The ALT normalization rate (86.7%) and HBV-DNA negative rate (90.0%) in the observation group were higher than those in the control group (66.7%, 70.0%). The scores of all dimensions of the chronic liver disease quality of life scale (CLDQ) in the observation group were significantly better than those in the control group, and the above differences were statistically significant (P Conclusion: “Case management + closed-loop management” dual nursing management mode can effectively improve the clinical cure of CHB period patients’ medication compliance, quality of life and nursing satisfaction, improving liver function and virology-related laboratory indicators of patients. The model is scientific and feasible, and has strong operability, which is worthy of clinical application.