TITLE:
Pancreatoduodenectomy in Locally Advanced Right Colon Cancer—Case Report and Literature Review
AUTHORS:
Carlos Hernández Brito, Stefan Zilli Hernández, Pedro Arredondo Ruiz, Omar Josué Herrera López, Luis Ángel Amezcua Toledo, Víctor Domínguez Osorio, Brenda Paola Sáenz Dávila, Óscar Mauricio López Gil, Luis Eduardo Méndez Turrubiates
KEYWORDS:
Pancreatoduodenectomy, Right Hemicolectomy with Pancreatoduodenectomy, Locally Advanced Colon Cancer, Locally Advanced Right-Sided Colon Cancer, En Bloc Multi-Organic Resection
JOURNAL NAME:
Surgical Science,
Vol.17 No.5,
May
9,
2026
ABSTRACT: Background: Pancreatoduodenectomy (PD) associated with colectomy is an uncommon procedure accounting for 2% - 11.5% of all PD, and only 6.2% are due to ascending colon cancer. Aim: Report an uncommon presentation of locally advanced colon cancer meriting an en bloc multi-organic resection describing current recommendations for its treatment. Case Presentation: A 29-year-old woman with a locally advanced right-sided colon cancer with duodenal infiltration treated with an en bloc multi-organic resection by right hemicolectomy with pancreatoduodenectomy and adjuvant chemotherapy. Conclusion: The best therapeutic approach for these patients has not been defined; initial surgical treatment is the most recommended option whenever it is possible to achieve an R0 resection.