TITLE:
Uterine and Adnexal Metastases Revealing an Occult Invasive Lobular Breast Carcinoma: A Case Report
AUTHORS:
Richie Ifuta, Lina Benfdil, Blaise Bonga, Milene Tshibola Nkashama, Houda Bentayaa, Ezéchiel Irangabiye, Mohamed Jalal, Sakher Mahdaoui, Houssine Boufettal, Naima Samouh
KEYWORDS:
Metastatic Breast Cancer, Occult Breast Cancer, Chronic Pelvic Pain, Uterine Metastasis, Breast Ultrasound-Mammography, Breast Examination, Ultrasound-Guided Biopsy, Hormone Therapy
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.16 No.4,
April
14,
2026
ABSTRACT: Uterine metastases from breast cancer represent a rare entity, most frequently associated with invasive lobular carcinoma, which is known for its distinctive metastatic tropism. We report the case of a 60-year-old postmenopausal woman who presented with chronic pelvic pain and deterioration of general condition. Initial imaging investigations, including abdominopelvic computed tomography and pelvic magnetic resonance imaging, revealed a large uterine mass associated with ascites and diffuse bone lesions, raising suspicion of a primary uterine malignancy with metastatic spread. Further diagnostic work-up subsequently identified an invasive lobular carcinoma of the left breast with a Luminal A immunohistochemical profile. Surgical management disclosed multiple metastatic sites, including the uterus, ovaries, peritoneum, and omentum, thereby confirming the mammary origin of the lesions. This case highlights the misleading clinical and radiological presentation of gynecological metastases from invasive lobular breast carcinoma, which may closely mimic a primary gynecologic malignancy. It underscores the importance of a multidisciplinary diagnostic approach and meticulous histopathological analysis to guide optimal therapeutic management.