TITLE:
Modified Vecchietti’s vaginoplasty with Remeex® system in patient with chronic graft-versus-host disease
AUTHORS:
Melado Vidales Laura, Muñoz Muñiz Mar, Santisteban Padro Javier
KEYWORDS:
Graft-Versus-Host Disease; Bone Marrow Transplantation; Vaginal Stenosis
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.2 No.1,
March
31,
2012
ABSTRACT: We present a case report of a chronic graft-versus-host disease manifestation in 33-year-old patient with an unusual complication of vaginal stenosis with complete obstruction after allogeneic bone marrow transplantation for myelocytic leukemia. The patient complained on a progressive dyspareunia and sexual intercourse inability. She has received hormone replacement therapy due to the ovarian failure after the chemotherapy treatment. The hormonal treatment was used in continuous combined manner and hematocolpos wasn’t seen during an abdominal ultrasound examination. The reconstructive surgery was performed by the modified Vecchietti’s neovagina technique with a Remeex® system after histological confirmation of main diagnosis. The immediate postoperative course was uneventful with gradual normalization of sexual function.