TITLE:
Early Result of Atrial Septal Defects Repair at Soavinandriana Hospital
AUTHORS:
Zakarimanana Lucas Randimbinirina, Tsirimalala Rajaobelison, Maharo Ramifehiarivo, Harijaona Fanomezantsoa Randrianandrianina, Rija Mikhaël Miandrisoa, Hariniaina Ravaoavy, Toky Mamin’ny Aina Rajaonanahary, Andriamihaja Jean-Claude Rakotoarisoa
KEYWORDS:
Atrial Septal Defects, Congenital Heart Disease, Surgery, Paediatrics
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.14 No.4,
March
27,
2026
ABSTRACT: Introduction: The surgical closure of an atrial septal defect (ASD) using cardiopulmonary bypass (CPB) was the first surgical repair of congenital heart disease (CHD) performed at Soavinandriana Hospital (Cenhosoa) in Antananarivo. This study aimed to report the initial results of our series of surgical closures of isolated ASDs performed at Soavinandriana Hospital. Materials and Methods: This retrospective case series reports early outcomes of surgical closure of isolated ostium secundum atrial septal defects (ASD) at Soavinandriana Hospital (Cehosoa), Madagascar, during 2024-2026. The authors analyze patient demographics, clinical presentation, echocardiography results, surgical techniques involving cardiopulmonary bypass time and immediate postoperative outcomes. Results: Eleven children and young adults who underwent surgical repair of ASD are reported in this study, including five males (45%) and six females (54%). The average age was 12.18 years. The mean weight was 31.36 kg. The main symptoms were a cardiac murmur (81%), recurrent lung infections (54%), and failure to thrive (27%). Echocardiography revealed an isolated ostium secundum ASDs (100%), large in 100% of cases with a mean diameter of 17.91 mm and associated with moderate pulmonary hypertension (81%). All ASD repairs were performed using conventional surgery and cardiopulmonary bypass (CPB). The ASDs were closed by using dacron patch (54%), autologous pericardial patch (36%) and direct suturing (9%). The mean CPB time was 77 minutes. The mean aortic cross-clamping time was 36 minutes. The postoperative success rate was 100%. Conclusion: Eleven patients underwent conventional repair on cardiopulmonary bypass with no mortality and one reported reoperation for postoperative bleeding. The manuscript positions this program as an important step toward local congenital heart surgery capacity and describes perioperative timings and short-term clinical outcomes.