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Winton, T., Livingston, R., Johnson, D., Rigas, J., Johnston, M., Butts, C., et al. (2005) Vinorelbine Plus Cisplatin vs. Observation in Resected Non-Small-Cell Lung Cancer. New England Journal of Medicine, 352, 2589-2597.
https://doi.org/10.1056/nejmoa043623

has been cited by the following article:

• TITLE: Complete Response in Inoperable Stage IIB Squamous Cell Lung Carcinoma after Sequential Radiotherapy and Chemotherapy: A Case Report and Review of the Literature

  AUTHORS: Gyursen Ziyafetova

  KEYWORDS: Non-Small Cell Lung Cancer, Chemotherapy, Radiotherapy

  JOURNAL NAME: Advances in Lung Cancer, Vol.15 No.1, March 19, 2026

  ABSTRACT: Background: This manuscript reports a stage IIB (cT3N0M0) squamous NSCLC case deemed inoperable and treated with definitive radiotherapy followed by carboplatin/paclitaxel, achieving complete metabolic response on PET/CT. The paper then reviews standard management options for stage II NSCLC, emphasizing multidisciplinary decision-making. The main message is that selected inoperable stage II patients may achieve durable control with sequential or concurrent chemoradiation. Patients and Methods: I present a case report of complete therapeutic response in inoperable stage IIB non-small cell lung carcinoma after sequential radiotherapy and chemotherapy and a review of literature. Results: Surgical resection is the cornerstone of treatment and the best option for achieving cure in patients with clinically operable Non-Small Cell Lung Cancer (NSCLC). In circumstances where surgical resection may not be feasible, patients may be presented at a Multidisciplinary Tumour Board for further discussion between surgery, medical oncology, radiation oncology, and palliative care. Whenever possible, patients should be considered for enrollment in clinical trials. Conclusions: Patients with stage II NSCLC who are inoperable or refuse surgery can also have long survival with concurrent or sequential radiotherapy and chemotherapy.