TITLE:
The Evolving Role of FDG-PET/CT in the Management of Cervical Cancer
AUTHORS:
Yuxin Zheng, Gang Cheng
KEYWORDS:
Cervical Cancer, 18F-FDG PET/CT, Clinical Management
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.14 No.3,
March
18,
2026
ABSTRACT: With the advancement of imaging technologies, the application of 18F-FDG PET/CT in the diagnosis and management of cervical cancer has garnered increasing attention. This article aims to review the clinical progress of PET/CT in the management of patients with cervical cancer. PET/CT has been widely used to assess lymph node status and distant metastases, and it is recommended for comprehensive staging in patients with locally advanced cervical cancer (FIGO stage ≥ IB3), enabling more rational planning and individualized treatment adjustments. Metabolic information from both the primary tumor and lymph nodes can be utilized for treatment response evaluation, prognosis prediction, and recurrence monitoring, ultimately helping to optimize the timing of interventions and improve survival outcomes. Meanwhile, the distribution of 18F-FDG uptake within the tumor can partially reflect tumor heterogeneity and provide complementary information to conventional semi-quantitative parameters. However, the clinical value of PET/CT in the management of patients with cervical cancer remains to be further validated.