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A. G. Rockall, S. A. Sohaib, M. G. Harisinghani, S. A. Babar, N. Singh, A. R. Jeyarajah, D. H. Oram, I. J. Jacobs, J. H. Shepherd and R. H. Reznek, “Diagnostic Performance of Nanoparticle-Enhanced Magnetic Resonance Imaging in the Diagnosis of Lymph Node Metastases in Patients with Endometrial and Cervical Cancer,” Journal of Clinical Oncology, Vol. 23, No. 12, 2005, pp. 2813-2821. doi:10.1200/JCO.2005.07.166

has been cited by the following article:

• TITLE: Diagnostic Accuracy of MRI in Primary Cervical Cancer

  AUTHORS: Giuliano Rigon, Cristina Vallone, Andrea Starita, Marco Flavio Michele Vismara, Pasquale Ialongo, Lorenza Putignani, Fabrizio Signore

  KEYWORDS: Cervical Cancer; MRI; Parametrial; Lymph node Involvement

  JOURNAL NAME: Open Journal of Radiology, Vol.2 No.1, March 30, 2012

  ABSTRACT: Introduction: Magnetic resonance imaging (MRI) studies obtained during the initial staging of patients affected by uterine cervical cancer were compared to the final histological report after surgery. Methods: Data were retrieved from published papers. Results: MRI detection of lymph node metastases shows a sensitivity of 49.3% (1209 patients) and a specificity of 87.7% (1182 patients). Parametrial involvement detection has 66.2% sensitivity (1288 patients) and 83.6% specificity (1282 patients). MRI tumor size evaluation shows significant error. Even detection of over 1 cm diameter primary tumor can fail. MRI appears promising in the detection of myometrial and endometrial involvement. Conclusions: Primary uterine cervical cancer evaluation with routine MRI has a limited accuracy especially in the detection of lymph node involvement and parametrial invasion. It is not sensitive enough to replace histology of dissected nodes and parametria. Tumor size estimation is imprecise. Detection of myometrial and endometrial invasion using MRI might be possible. Awareness of MRI limitations is crucial in primary cervical cancer staging.