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D. E. Tabor, J. B. Kim, B. M. Spiegelman and P. A. Edwards, “Identification of Conserved Cis-Elements and Transcription Factors Required for Sterol-Regulated Transcription of Stearoyl-CoA Desaturase 1 and 2,” Journal of Biological Chemistry, Vol. 274, 1999, pp. 20603-20610. doi:10.1074/jbc.274.29.20603

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• TITLE: Olive and Corn Oil Enriched Diets Changed the Phospholipid Fatty Acid Composition in Mice Liver after One-Thirds Hepatectomy

  AUTHORS: Jasminka Giacometti, Alena Buretic Tomljanovic, Cedomila Milin, Mira Cuk, Biserka Radosevic Stasic

  KEYWORDS: Fatty Acids; Phospholipids; One-Thirds Partial Hepatectomy; Olive Oil; Corn Oil; Diet

  JOURNAL NAME: Food and Nutrition Sciences, Vol.3 No.2, February 27, 2012

  ABSTRACT: We examined the effect of dietary fats on the kinetics of liver regeneration after one-third partial hepatectomy (PH) in male Balb/c mice. Corn and olive supplemented diets were chosen as a model of n-6 and n-9 diets. Phospholipid fatty acids were determined by gas chromatography (GC) after previous fractionation by solid-phase extraction using aminopropyl (NH2) column, and data were analysed by nonparametric Kruskal-Wallis test. Diet enriched with corn and olive oil did not affect the balance of lipid disorders during liver regeneration after 1/3 PH. Desaturases activity direction has changed depending on the used diet. The key role in the alteration of the polar fatty acids profile at all stages of liver regeneration and examined dietary fats is played by activity of stearoyl-CoA desaturase (SCD).