TITLE:
Acute Necrotizing Encephalopathy Related to Non-Influenza Viruses in Rare Adult Cases
AUTHORS:
Bangfeng Li, Yongjun Peng
KEYWORDS:
Acute Necrotizing Encephalopathy, Viral Infection, Cytokine Storm, MRI
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.14 No.3,
March
6,
2026
ABSTRACT: Acute necrotizing encephalopathy (ANE) is a rare, rapidly progressive, and severe immune-mediated neurological disorder that frequently leads to severe neurological sequelae or mortality. Viral infection represents a common pathogenic factor, while cytokine storm constitutes the primary pathogenic mechanism. ANE is a distinct clinical entity characterized by specific clinical and imaging features. Immunomodulatory therapy and anti-cytokine interventions represent effective treatment strategies for ANE.