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Rahaman, M.S., Rahman, M.M., Mise, N., Sikder, M.T., Ichihara, G., Uddin, M.K., et al. (2021) Environmental Arsenic Exposure and Its Contribution to Human Diseases, Toxicity Mechanism and Management. Environmental Pollution, 289, Article 117940.
https://doi.org/10.1016/j.envpol.2021.117940

has been cited by the following article:

• TITLE: Arsenic Encephalopathy Associated with Excessive Seafood Consumption: A Case Report

  AUTHORS: Sandra Johnson

  KEYWORDS: Arsenic Toxicity, Encephalopathy, Seafood, Organic Arsenic, Inorganic Arsenic, Altered Mental Status

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.15 No.3, February 28, 2026

  ABSTRACT: Arsenic toxicity is an uncommon and frequently underrecognized cause of subacute encephalopathy. Diagnosis requires careful integration of exposure history, clinical findings, and laboratory testing, particularly because dietary sources such as seafood can elevate urinary arsenic levels without causing true toxicity. We report the case of a 39-year-old woman presenting with progressive cognitive impairment and functional decline who was found to have markedly elevated urinary arsenic levels in the setting of excessive seaweed consumption. Extensive evaluation for infectious, autoimmune, metabolic, and structural causes of altered mental status was unrevealing. Her cognitive function steadily improved with supportive care and elimination of dietary exposure, without chelation therapy. This case highlights the diagnostic challenges in interpreting elevated urinary arsenic levels, the contribution of seafood to total arsenic measurements, and the critical role of arsenic speciation in clinical interpretation and management.