TITLE:
Prevalence and Factors Associated with Hepatitis B Virus Carriage among Blood Donors at the Coyah Hospital Blood Transfusion Unit (Guinea)
AUTHORS:
Ansoumane Oulare, Ibrahima Sayon Cissé, Tanou Valdez Bah, Saran Camara, Baba Kallé, Amadou Sekou Camara, Alseny Diallo, Mamady Diakité
KEYWORDS:
Hepatitis B Virus, Prevalence, Guinea
JOURNAL NAME:
Open Journal of Blood Diseases,
Vol.16 No.1,
February
13,
2026
ABSTRACT: Introduction: This study aims to determine the prevalence of HBV and identify associated demographic and clinical risk factors among blood donors. Methods: This was a cross-sectional study with an analytical focus. Donor demographic data were collected and multivariate logistic regression was performed to identify predictors of HBV positivity. Results: In univariate analysis, age, level of education, risky sexual behaviors, and HIV infection were significantly associated with the outcome of interest. Schooled donors had a significantly lower likelihood compared with non-schooled donors (OR = 0.53; 95% CI: 0.32 - 0.87; p = 0.013), suggesting a protective effect of education. In multivariate analysis, after adjustment for potential confounding factors, age (31 - 40 years and 51 - 60 years), risky sexual behaviors, and HIV infection remained significantly associated with the outcome, while education persisted as an independent protective factor (OR = 0.36; 95% CI: 0.20 - 0.63; p Conclusion: Demographic and clinical factors, such as age, educational level, risky sexual behaviors, and HIV positivity, are significant determinants of HbsAg positivity in blood donors. These results highlight the importance of taking these factors into account in the management of blood donations.