TITLE:
Medication Safety after Hospital Discharge among Older Adults with Chronic Diseases in China: Risk Factors and Management Strategies
AUTHORS:
Zhangyan He, Rumeng Mao
KEYWORDS:
Older Adults with Chronic Diseases, Oral Medications, Post-Discharge Patients, Medication Safety, Medication Management
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.14 No.2,
February
3,
2026
ABSTRACT: With accelerating population aging, the safety of oral medication among older patients with chronic diseases after hospital discharge has become a major public health challenge. Age-related physiological decline, polypharmacy, and limited health literacy—coupled with inadequate professional guidance and insufficient social support—collectively expose this population to a heightened risk of medication errors, drug-drug interactions, and poor adherence. This review synthesizes recent evidence on risk factors and emerging management strategies. At the patient level, standardized nursing protocols and stratified management models (e.g., red-yellow-green risk classification) have been introduced to improve adherence. At the institutional level, multidisci plinary collaboration has been leveraged to optimize prescribing and medication counseling. At the societal level, community-based and family-supported care models are being promoted to strengthen continuity of medication management. However, heterogeneous effects of standardized interventions, gaps in primary-care services, and limited technological capacity continue to constrain real-world implementation. Strengthening pharmacist-led services at the primary-care level, establishing an integrated “home-community-hospital” coordination network, and enhancing policy support may help bridge current practice gaps and provide an evidence-based foundation for longitudinal management of older adults with chronic diseases.