TITLE:
Cloves Syndrome: A Case Series of a Rare Syndrome
AUTHORS:
Warigbani Pieterson, Edem Anyigba, Omane Acheamfour Okrah, Hafisatu Gbadamosi, Elleisabeth Pieterson
KEYWORDS:
Overgrowth Syndrome, CLOVES, Vascular Anomalies, Clinical Symptomatology, Imaging Spectrum
JOURNAL NAME:
Modern Plastic Surgery,
Vol.16 No.1,
January
29,
2026
ABSTRACT: “Overgrowth” syndrome generally describes abnormal growth patterns in the milieu of a constellation of other symptoms and signs. CLOVES (Congenital Lipomatous asymmetric overgrowth of the trunk with lymphatic, capillary, venous and combined-type vascular malformations, epidermal naevi, scoliosis/ skeletal and spinal anomalies) is a segmental overgrowth syndrome with vascular anomalies. The clinical symptomatology is thus very variable and based on the involved systems. This groundbreaking series seeks to document the clinical and imaging spectrum of findings in these four children, which will be the first of its kind in Ghana, West Africa.