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Lin, N.C., Vu Nguyen, T.H., Shih, Y.H., Chen, Y.H., Shen, Y.W., et al. (2024) Association of Higher Transient Receptor Potential Melastatin 8 Expression with Higher Tumor Histologic Grades, Lymph Node Metastasis, Risk Factors, and Worse Survival in Patients with Head and Neck Squamous Cell Carcinoma. Journal of Dental Sciences, 19, 492-501.
https://doi.org/10.1016/j.jds.2023.09.007

has been cited by the following article:

• TITLE: Research Progress of Transient Receptor Potential Melastatin Family in Head and Neck Squamous Cell Carcinoma

  AUTHORS: Shuqi Lao, Mingfang Xu

  KEYWORDS: TRPM Channels, Head-And-Neck Squamous Cell Carcinoma, Biomarker, Therapeutic Target

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.14 No.2, January 29, 2026

  ABSTRACT: Head and neck squamous cell carcinoma (HNSCC) is the seventh leading cause of mortality among malignant tumors globally. Patients face a poor prognosis and low five-year survival rate due to late-stage diagnosis, high recurrence rate, and metastasis rate. Calcium ion channels are critically involved in tumorigenesis, development, and metastasis, participating in mechanisms such as cell proliferation, apoptosis, invasion, migration, and regulation of the tumor microenvironment. Among these channels, the transient receptor potential melastatin ion channel (TRPM) has been rapidly studied in HNSCC in recent years. Evidence suggests that TRPM channels play both promoting and suppressing roles in the progression of HNSCC, highlighting their potential as diagnostic and prognostic biomarkers, as well as therapeutic targets. This review summarizes the research findings of the TRPM family in the field of HNSCC, providing new insights into prognosis and targeted molecular therapy.