Article citationsMore>>

Goldenberg, D., Begum, S., Westra, W.H., Khan, Z., Sciubba, J., Pai, S.I., Califano, J.A., Tufano, R.P. and Koch, W.M. (2008) Cystic lymph node metastasis in patients with head and neck cancer: An HPV-associated phenomenon. Head Neck, 30, 898-903. doi:10.1002/hed.20796

has been cited by the following article:

• TITLE: Absence of adjuvant radiotherapy may be an additional criteria in diagnosing a branchiogenic squamous cell carcinoma: A case report

  AUTHORS: Alexandre Anesi, Giuseppe Pollastri, Vincenzo Bondì, Sara Barberini, Luigi Chiarini

  KEYWORDS: Branchial Cleft Cyst; Branchial Cyst; Branchiogenic Carcinoma; Malignant Branchioma; Cystic Cervical Lymph Node Metastasis

  JOURNAL NAME: Open Journal of Stomatology, Vol.2 No.1, March 28, 2012

  ABSTRACT: Branchiogenic carcinoma is extremely rare. The majority of branchiogenic carcinomas are cystic metastases originating in the tonsils, and not true carcinomas arising in a branchial cleft cyst. Isolated cystic neck lesions necessitate a thorough search for a primary tumor, as with other occult primaries presenting with cervical metastases. As the existence of primary branchiogenic carcinoma is controversial, Martin and colleagues and then Khafif and coworkers established a series of widely accepted criteria to recognize this type of carcinoma. We report a case of a large cervical mass, consistent with a branchiogenic carcinoma of the second branchial arch. The patient underwent excision of the neck mass through a radical neck dissection. The cyst wall was found to have squamous cell carcinoma arising from the benign epithelium. Follow-up at 7 years revealed no evidence of recurrence. All diagnostic criteria for a true branchiogenic carcinoma were met in this case. The absence of adjuvant irradiation is a further confirmation that the mass is not a cystic node metastasis but a carcinoma arised from within a branchial cleft cyst.