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Chu, G., Li, P., Zhao, Q., He, R. and Zhao, Y. (2023) Mutation Spectrum of Kallmann Syndrome: Identification of Five Novel Mutations across ANOS1 and FGFR1. Reproductive Biology and Endocrinology, 21, Article No. 23.
https://doi.org/10.1186/s12958-023-01074-w

has been cited by the following article:

• TITLE: Kallmann Syndrome: Review of Two Cases in Brothers

  AUTHORS: Djaury Dadji, Ildjima Kadallah, Adrienne Ngaringuem, Ntsoli Gaelle, Djohara Barka, Dessainbe Djoui, Micondo Kouamé Hervé

  KEYWORDS: Kallmann Syndrome, N’Djamena, Chad

  JOURNAL NAME: Open Journal of Pediatrics, Vol.16 No.1, January 26, 2026

  ABSTRACT: Background: Kallmann syndrome is a rare genetic disorder characterized by congenital hypogonadotropic hypogonadism associated with anosmia. We report two cases of Kallmann syndrome in two brothers followed at the University Mother and Child Hospital of N’Djamena. Case Presentation: An 18-year-old young man presented with micropenis (40 mm), bilateral cryptorchidism, anosmia, and severe growth retardation (height 146 cm, −4 SD). Biological investigations revealed hypogonadotropic hypogonadism (FSH: 0.42 IU/ml, LH 2). After 5 injections, significant clinical improvement was observed: increase in penile length to 70 mm and 65 mm respectively, with regular erections, ejaculation, and testicular descent. Conclusion: Kallmann syndrome, although rare, warrants systematic consideration in adolescents presenting with delayed puberty, anosmia, and micropenis.