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Papachristodoulou, E., Graef, E., Magliulo, D. and Kyttaris, V. (2023) Prevalence and Clinical Significance of Lymphadenopathy and Its Histological Subtypes in Patients with Systemic Lupus Erythematosus: A Retrospective Cohort Study. Rheumatology International, 43, 1277-1286.
https://doi.org/10.1007/s00296-023-05331-4

has been cited by the following article:

• TITLE: Massive Generalized Lymphadenopathy Due to Systemic Lupus Erythematosus

  AUTHORS: Kamel El-Reshaid, Emad Abdullah, Sami Aldaoud, Silvia Contu

  KEYWORDS: Systemic Lupus Erythematosus, Lymphoma, Mycophenolate, Rituximab, Anti-Phospholipid Syndrome, Lymphadenopathy, PET Scan

  JOURNAL NAME: Open Journal of Nephrology, Vol.16 No.1, January 14, 2026

  ABSTRACT: Background: Massive generalized lymphadenopathy (MGL) as an initial manifestation of systemic lupus erythematosus (SLE) is rare. The Case: A previously healthy 18-year-old man presented with MGL for 1 month. Subsequently, he developed fever, hypertension, fluid overload, and left abdominal pain. He had hemoglobin 89 g/L, serum creatinine 168 umol/L, serum albumin 29 g/L, prolonged activated partial thromboplastin time, heavy proteinuria, and hematuria. Fused PET/CT scanning showed hypermetabolic peripheral and internal MGL with splenic and right kidney infarctions. Autoimmune tests showed very low serum complements 3 and 4 with high titers of ANA 1/640 (N: 1/40) and anti-dsDNA 666 IU/ml (N: In Conclusion: SLE can present with MGL.