Article citationsMore>>

Napolitano, M., Siragusa, S. and Mariani, G. (2017) Factor VII Deficiency: Clinical Phenotype, Genotype and Therapy. Journal of Clinical Medicine, 6, Article 38.
https://doi.org/10.3390/jcm6040038

has been cited by the following article:

• TITLE: Congenital Factor VII Deficiency Revealed in the Neonatal Period: A Case Report at CHNEAR

  AUTHORS: Maryame Aida Kane, Awa Kane, Ibrahima Diop, Mame Awa Ndao, Sokhna Aissatou Touré, Sadio Konaté, Fatima Zahra Sahib, Amadou Sow, Aminata Mbaye, Aida Sarr, Souleye Sow, Abdou Aziz Faye, Mame Fama Niang, Diary Sow, Djibril Boiro, Indou Deme Ly, Babacar Niang, Abou Ba, Idrissa Demba Ba, Pape Moctar Faye, Amadou Lamine Fall, Saliou Diop, Ousmane Ndiaye

  KEYWORDS: Factor VII, Neonatal Hemorrhage, Congenital, Autosomal Recessive, Hemostasis

  JOURNAL NAME: Open Journal of Pediatrics, Vol.16 No.1, January 13, 2026

  ABSTRACT: Congenital factor VII deficiency is a rare, autosomal recessive disorder with an estimated prevalence of 1 in 1,000,000. We report the case of a female newborn, born to second-degree consanguineous parents, admitted at 22 days of age for management of a subarachnoid hemorrhage. Hemostasis testing revealed a prothrombin time (PT) of 16%, with a preserved activated partial thromboplastin time (aPTT). Coagulation testing demonstrated an isolated factor VII deficiency. Through this case, we highlight the clinical, biological, and therapeutic characteristics of this anomaly during the neonatal period.