TITLE:
Surgical Site Infections at CHNU of Fann: Bacteriological Characterization and Antibiotic Susceptibility Profiles of the Isolates
AUTHORS:
Fatoumata Diallo, Mariama Djiba, Aissatou Gaye, Madiagne Der, Baidy Dièye, Aissatou Ahmat Niang, Amadou Diop, Habibou Sarr, Mouhamadou Lamine Dia
KEYWORDS:
Infection, Surgery, Bacteria, Resistance
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.15 No.4,
December
31,
2025
ABSTRACT: Introduction: Surgical site infections (SSIs) are a common and serious complication in hospital settings, particularly following complex procedures such as thoracic and cardiovascular surgery. Methods: We conducted a six-month retrospective study (January-June 2023) in the Bacteriology-Virology Laboratory of CHNU de Fann, including 75 patients who developed a surgical site infection. Suspected clinical specimens were collected and analyzed to identify the causative bacteria and their antimicrobial resistance profiles. Results: The prevalence of SSIs in our cohort was high (68%, 51/75 positive samples). The mean age of patients was 40.25 years (range: 4 - 83). SSIs were particularly frequent in thoracic and cardiovascular surgery. Enterobacterales were the most frequently isolated pathogens (33 cases), predominantly Enterobacter spp. (16 cases) and Klebsiella pneumoniae (8 cases); most were extended-spectrum β-lactamase (ESBL) producers (54.54%). Non-fermenting Gram-negative bacilli were mainly represented by Pseudomonas spp. (17 cases). Gram-positive cocci were primarily Staphylococcus aureus (6 cases), most of which were high-level penicillinase producers. These findings highlight the urgent need to revise empirical antibiotic protocols and to strengthen prevention strategies in response to the high prevalence of ESBL-producing Enterobacterales.