Article citationsMore>>

T.-H. Chun, K. B. Hotary, F. Sabeh, A. R. Saltiel, E. D. Allen and S. J. Weiss, “A Pericellular Collagenase Directs the 3-Dimensional Development of White Adipose Tissue,” Cell, Vol. 125, No. 3, 2006, pp. 577-591. doi:10.1016/j.cell.2006.02.050

has been cited by the following article:

• TITLE: The Pathophysiology of Cellulite: Can the Puzzle Eventually Be Solved?

  AUTHORS: Ilja Kruglikov

  KEYWORDS: Cellulite; Pathophysiology; Adipose Fibrosis; Hyaluronan; Optimal Treatment Strategy

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.2 No.1, March 28, 2012

  ABSTRACT: The pathophysiology of cellulite is still largely unknown. Here, we propose a new pathophysiology that connects the development of cellulite with several newly-discovered hallmarks of white adipose tissue. According to this theory, cellulite appears in hypertrophic fat tissue that is associated with overproduction of low molecular weight hyaluronan (HA). This can induce different types of fibrosis, producing inhomogeneous spatial tension in the tissue. This pathophysiology serves to explain the most well known peculiarities of cellulite appearance as well as to formulate the theoretically optimal cellulite treatment strategy.