TITLE:
Plant-Based Biopesticide from Madagascar Melia azedarach
AUTHORS:
Ihanta Vololonirina Rahariseheno, Richard Randrianandrasana, Herimalala Marie Raharitsiadiana, Caitlyn Olivia Agee, Wendy Lynn Fletcher, Eric Hajaniriana Andrianasolo
KEYWORDS:
Melia azedarach, Biopesticides, Azadirachtin, Meliatoxin, Antifeedant
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.16 No.1,
December
22,
2025
ABSTRACT: The growing utilization of natural pesticides from plants increases the need to develop new alternative sources. The Madagascar Melia azedarach presents the advantage of producing Azadirachtin D, one of the bioactive molecules that functions as an antifeedant, repellent, insecticide, and growth regulator. The plant, which originated from Madagascar does not biosynthesize the toxic molecule Meliatoxin A and its derivatives, making it an interesting alternative for plant-based biopesticide. This work presents the origin, chemical analyses, and an example of the application of a plant-based biopesticide from the leaves of Melia azedarach.