TITLE:
Challenges in the Diagnosis and Treatment of Polycystic Ovary Syndrome (PCOS) in Adolescents: A Narrative Review
AUTHORS:
Sandrine Modia Putshu, Jean-Didier Bosenge-Nguma, Antoine Modia O’yandjo, Arsène Mputu Lobo, Justin Mboloko Esimo
KEYWORDS:
Polycystic Ovary Syndrome, Adolescent, Anovulation, Hyperandrogenic
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.15 No.12,
December
12,
2025
ABSTRACT: Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of childbearing age, typified by hyperandrogenism and oligo- or anovulation. The diagnostic criteria for PCOS are well established for adult women. In adolescents, the clinical manifestations of PCOS are generally regarded as normal, attributable to the physiological changes associated with puberty. Patients diagnosed with PCOS are often concomitantly affected by other medical conditions, including obesity, insulin resistance, hypertension, metabolic syndrome, and an elevated risk of developing diabetes. Given the profound implications of metabolic impairment in PCOS, it is imperative to make an accurate diagnosis and manage these aspects. However, there is currently no international consensus on the diagnosis and management of PCOS in adolescents. A comprehensive review of the extant literature on the subject is imperative to inform the development of the recommendations. This objective constitutes the underlying rationale for the present literature review.