TITLE:
A Case Study on Pain Management and Comfort Care in a Patient with Advanced Osteosarcoma
AUTHORS:
Yonge Gu, Wenxuan Jiang
KEYWORDS:
Advanced Osteosarcoma, Pain Management, Comfort Care
JOURNAL NAME:
Open Journal of Nursing,
Vol.15 No.11,
November
20,
2025
ABSTRACT: This study presents a case report on pain management and comfort care practices for a 52-year-old male patient with advanced osteosarcoma recurrence and systemic metastasis. The patient presented with persistent severe pain (NRS 7 - 8) accompanied by anxiety and sleep disturbances upon admission. The medical team implemented a multimodal analgesia regimen using oxycodone (40 mg q12h) as the foundation, combined with celecoxib (200 mg qd) and gabapentin (300 mg tid), achieving significant pain relief (NRS reduced to 3 - 4). Concurrent multidimensional comfort care measures including positional management, local heat therapy, music therapy, and psychological intervention were applied. The patient’s HADS anxiety score decreased from 15 to 9, with increased sleep duration by 2 hours. Assessment using the EORTC QLQ-C30 scale revealed a 57% improvement in overall quality of life, with the most notable enhancement in emotional function (+82%). The contribution rate of nursing interventions to functional recovery (42%) exceeded that of monotherapy (31%). Through systematic family education programs, standardized home care compliance rates increased from 48% to 89%, establishing an effective home-hospital collaboration model. This case demonstrates that multimodal analgesia based on WHO’s three-step principles combined with personalized comfort care can effectively improve quality of life in advanced osteosarcoma patients. Innovatively, adopting a “symptom cluster” management approach, dynamic monitoring and timely adjustment of interventions provided comprehensive symptom control for terminal patients. The results have important reference value for improving the practice of palliative care in advanced cancer patients, suggesting that multi-disciplinary collaboration and family nursing support system should be strengthened in the future.