TITLE:
Clinical Application Analysis of Vivity Intraocular Lens
AUTHORS:
Ying Chen, Jinhua Wang, Bing Wu
KEYWORDS:
Vivity Intraocular Lens, Extended Depth of Focus Intraocular Lens (EDOF), Refractive Cataract Surgery, Visual Quality, Spectacle Independence Rate, Optical Disturbance, Clinical Application Optimization
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.13 No.11,
November
14,
2025
ABSTRACT: The demand for full-range visual quality in refractive cataract surgery has driven the development of non-diffractive extended depth of focus (EDOF) intraocular lenses (IOLs). Vivity achieves depth of focus extension through the X-WaveTM wavefront shaping technology (a 2.2 mm central dual smooth surface transition element). Its hydrophobic acrylate material reduces the incidence of posterior capsule opacification (PCO) and filters harmful blue light, while the modified L-haptic design ensures capsular bag centration. Clinical data shows that in both the cataract cohort and the refractive lens exchange (RLE) cohort with bilateral Vivity implantation, the uncorrected distance visual acuity (UDVA) and uncorrected intermediate visual acuity (UIVA) are excellent, while the uncorrected near visual acuity (UNVA) is adequate for daily needs. The spectacle independence rates for distance, intermediate, and near vision were 87.9%/86.6%, 77.6%/79.3%, and 46.1%/59.8% (cataract/RLE cohorts), respectively. Additionally, 91.8%/84.1% of patients reported no visual disturbances, and the satisfaction rate exceeded 85%. Clinical comparisons indicate that Vivity exhibits optical quality close to that of monofocal IOLs, a longer depth of focus than monofocal IOLs, fewer visual disturbances than diffractive multifocal IOLs, a relatively wide depth of focus range, and excellent resistance to tilt and decentration. However, Vivity has limitations, including insufficient fine near vision (most patients require low-power near vision add-ons), significant pupil dependence, and a lack of long-term data beyond 3 years. Strategies to optimize its application include adopting a micro-monovision design to improve near vision and adapting it for patients with mild epiretinal membranes and early age-related macular degeneration (AMD). Conclusion: Vivity is a recommended option for patients who require distance and intermediate vision and cannot tolerate optical disturbances from diffractive IOLs. However, in clinical practice, precise selection based on ocular parameters and visual needs is essential.