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Chou, K.L., Stacy, M., Simuni, T., Miyasaki, J., Oertel, W.H., Sethi, K., et al. (2018) The Spectrum of “Off” in Parkinson’s Disease: What Have We Learned over 40 Years? Parkinsonism & Related Disorders, 51, 9-16.
https://doi.org/10.1016/j.parkreldis.2018.02.001

has been cited by the following article:

• TITLE: Monitoring and Graphing Selected Motor and Non-Motor Symptom Fluctuations in a 72-Year-Old Parkinson’s Patient: A Caregiver Perspective

  AUTHORS: Julia Karpinska

  KEYWORDS: Parkinson’s Disease, Motor and Non-Motor Symptoms, Diurnal Symptoms’ Fluctuations, Carbidopa/Levodopa

  JOURNAL NAME: Advances in Parkinson's Disease, Vol.14 No.4, October 31, 2025

  ABSTRACT: Parkinson’s Disease (PD) is characterized by a spectrum of symptoms, including movement disabilities and non-motor neuropsychiatric, sleep, sensory, and autonomic complications. Fluctuations of symptoms in PD create an additional burden for patients and, due to difficulties in their recognition and tracking, impediments to optimal management of the disease. This case report details the daily monitoring and graphing of motor and non-motor symptoms in a 72-year-old Parkinson’s disease patient. Following a reduction in the patient’s carbidopa/levodopa dosage, a caregiver used a custom observational scale to chart symptom fluctuations over three weeks. The study finds that the medication adjustment correlated with an attenuation of symptom fluctuations, suggesting this caregiver-led method may be a useful tool for tracking treatment effects in PD management.