TITLE:
Maternal-Fetal Prognosis of Cesarean Section after Induction of Labor by Misoprostol in the Gynecology-Obstetrics Department of the Ignace Deen University Hospital Center in Guinea
AUTHORS:
Ibrahima Koussy Bah, Aboubacar Fodé Momo Soumah, Oumou Hawa Bah, Alpha Ibrahima Balde, Abdoulaye Bah, Kabinet Camara, Laouratou Diallo, Yaya Diallo, Abdourahamane Diallo, Telly Sy
KEYWORDS:
Induction of Labor, Cesarean Section, Misoprostol, CHU Ignace Deen
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.15 No.10,
October
31,
2025
ABSTRACT: Introduction: The objective of this work was to evaluate the maternal and fetal prognosis of cesarean section after induction of labor with misoprostol at the University Hospital of Conakry during the study. Material and Methods: We conducted a descriptive and analytical study lasting 6 months on pregnant women admitted to the department who had undergone artificial induction and those who had spontaneous induction. Results: The frequency of induction was 3.61%. The age group 26 - 35 years (52.2%), married (89.1%), unschooled (52.2%), self-employed (45.7%), and nulliparous women (56.52%) were the most concerned. Severe preeclampsia (45.7%) and post-term pregnancy (26.1%) were the main indications for induction. Patients who had received 2 doses of misoprostol were the most frequent (58.7%). There was a significant association between artificial induction with misoprostol and parietal suppuration: OR: 95% CI: 0.047 (0.011 - 0.19), P = 0.00; postpartum hemorrhage: OR: 95% CI: 0.045 (0.011 - 0.19), P = 0.00; uterine rupture: OR: 95% CI: 0.011 (0.00011 - 0.18), P = 0.00; and maternal death: OR: 95% CI: 0.011 (0.0007 - 0.18), P = 0.000. As for neonatal prognosis, we recorded 2 cases of neonatal deaths (4.35% versus 2.17%). Conclusion: The majority of patients had received two doses of misoprostol. The study revealed a significant association between its use and the occurrence of maternal complications, notably uterine rupture, postpartum hemorrhage, parietal suppuration, and maternal death. On the fetal level, a link was observed between a morbid Apgar score and fetal mortality. Further research is needed to define optimal and safe doses.