TITLE:
Glycidic Cues for Tissue Engineering: Synthesis and Characterization
AUTHORS:
Fatma Cetin Telli
KEYWORDS:
Collagen, Glycidic Cue, Multifunctional Biomolecule, Bioconjugation, Tissue Engineering
JOURNAL NAME:
Journal of Biomedical Science and Engineering,
Vol.18 No.10,
October
29,
2025
ABSTRACT: The bioactivity of materials can be enhanced by incorporating adhesive cues and regulatory molecules. Carbohydrates are essential for numerous biological recognition processes. Recent evidence suggests that collagen glycosylation is crucial for maintaining the equilibrium between collagen deposition and turnover, with several implications for healthy and pathological conditions. In this study, we synthesized small glycidic cues for enrichment with collagen. A relevant factor for successful biomaterial decoration pertains to the selection of appropriate chemistry. This research is strongly motivated by the need for innovative biomaterials in cartilage tissue engineering, especially for repairing osteoarthritis defects.