Article citationsMore>>

Huang, D.Q., Singal, A.G., Kono, Y., Tan, D.J.H., El-Serag, H.B. and Loomba, R. (2022) Changing Global Epidemiology of Liver Cancer from 2010 to 2019: NASH Is the Fastest Growing Cause of Liver Cancer. Cell Metabolism, 34, 969-977.e2.
https://doi.org/10.1016/j.cmet.2022.05.003

has been cited by the following article:

• TITLE: Complex of Amino Acids, Choline, and B-Group Vitamins for the Improvement of Early-Stage Metabolic Dysfunction-Associated Steatotic Liver Disease

  AUTHORS: Natalija Murane, Klinta Luize Sprudza, Jelena Ivanova, Polina Zalizko

  KEYWORDS: MASLD, MASH, Amino Acids, B-Group Vitamins

  JOURNAL NAME: Health, Vol.17 No.10, October 23, 2025

  ABSTRACT: Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most common cause of chronic liver disease worldwide, affecting an estimated 25% of the global population. Up to 80% of individuals with hepatic steatosis remain asymptomatic and may show no biochemical abnormalities, meaning that MASLD is frequently silent until complications occur, which makes early diagnosis challenging. Lifestyle modification, including dietary changes, regular physical activity, and sustained weight reduction, is the cornerstone of MASLD management. At present, however, there is still no universally standardized pharmacological treatment for MASLD all over the world, and management continues to rely primarily on lifestyle modification. The amino acids and B-group vitamin complex is expected to be effective in treating the early stage of steatohepatosis and steatohepatitis, reducing aminotransferases levels and decreasing liver fat cell accumulation.