TITLE:
Efficacy of Mixture of Osteon II Collagen with Hyaluronic Acid for Immediate Implant Placement in Chronic Infected Socket (Clinical and Radiographic Study)
AUTHORS:
Hassan Ali Hassan Abd El-Aziz Adam, Ahmed Omar Ahmed, Abdel Aziz Baiomy Abdullah
KEYWORDS:
Osteon II, Hyaluronic Acid, Immediate, Implant, Bone
JOURNAL NAME:
Open Journal of Stomatology,
Vol.15 No.9,
September
25,
2025
ABSTRACT: Objective: This randomized controlled trial (RCT) was conducted to compare the effectiveness of Osteon II collagen with hyaluronic acid versus Osteon II collagen alone for immediate implant placement in infected sockets. Patients and Methods: This study was conducted on 20 patients at the Department of Oral and Maxillofacial Surgery at Al-Azhar University’s Assiut Branch and they were divided into; Group Ι (control): 10 patients who received immediate dental implants with Osteon II collagen graft only and Group II: 10 patients who received immediate dental implants with Osteon II collagen with Hyaluronic acid graft. Results: Regarding Modified Bleeding Index (MBI), there was no statistically significant difference between 6 months and 9 months in Group I, while there was a statistically significant difference in Group II. There was no statistically significant difference at 6 months and 9 months between Group I and Group II. Regarding marginal bone loss (MBL), in Group I, there was a statistically significant difference between baseline, 3 months and 6 months. In Group II, there was a statistically significant difference between baseline, 3 months and 6 months. There was no statistically significant difference at baseline and 3 months between Group I and Group II. There was a statistically significant difference at 6 months between Group I and Group II. Conclusion: Adding hyaluronic acid to Osteon II Collagen contributes to increased bone density, improved implant stability, a reduction in MBL, and a shorter healing time.