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Alom, M.Z., Hasan, M., Yakopcic, C., Taha, T.M. and Asari, V.K. (2018) Recurrent Residual Convolutional Neural Network Based on U-Net (R2U-Net) for Medical Image Segmentation. arXiv: 1802.06955.

has been cited by the following article:

• TITLE: Enhanced Liver Tumor Detection in CT Images Using 3D U-Net and Bat Algorithm for Hyperparameter Optimization

  AUTHORS: Nastaran Ghorbani, Bitasadat Jamshidi, Mohsen Rostamy-Malkhalifeh

  KEYWORDS: Liver Tumor Segmentation, 3D U-Net, Bat Algorithm, Deep Learning, CT Imaging, Medical Image Analysis, Hyperparameter Optimization

  JOURNAL NAME: Open Journal of Medical Imaging, Vol.15 No.3, September 25, 2025

  ABSTRACT: Liver cancer is one of the most prevalent and lethal forms of cancer, making early detection crucial for effective treatment. This paper introduces a novel approach for automated liver tumor segmentation in computed tomography (CT) images by integrating a 3D U-Net architecture with the Bat Algorithm for hyperparameter optimization. The method enhances segmentation accuracy and robustness by intelligently optimizing key parameters like the learning rate and batch size. Evaluated on a publicly available dataset, our model demonstrates a strong ability to balance precision and recall, with a high F1-score at lower prediction thresholds. This is particularly valuable for clinical diagnostics, where ensuring no potential tumors are missed is paramount. Our work contributes to the field of medical image analysis by demonstrating that the synergy between a robust deep learning architecture and a metaheuristic optimization algorithm can yield a highly effective solution for complex segmentation tasks.