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Michaud, V. and Turgeon, J. (2010) Assessment of Competitive and Mechanism-Based Inhibition by Clarithromycin: Use of Domperidone as a CYP3A Probe-Drug Substrate and Various Enzymatic Sources Including a New Cell-Based Assay with Freshly Isolated Human Hepatocytes. Drug Metabolism Letters, 4, 69-76.
https://doi.org/10.2174/187231210791292717

has been cited by the following article:

• TITLE: Recognition and Management of Clarithromycin-Induced Non-Vertiginous Dizziness in an Elderly Patient with Pertussis

  AUTHORS: Enoch Chi Ngai Lim, Chi Eung Danforn Lim

  KEYWORDS: Clarithromycin, Side Effects, Dizziness

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.13 No.9, September 11, 2025

  ABSTRACT: An 85-year-old woman developed persistent mild dizziness without vertigo three days after starting clarithromycin 500 mg twice daily for serology-confirmed pertussis. The dizziness did not improve with prochlorperazine and fully resolved within three days of switching to betahistine. Diagnostic workup was unremarkable, including a normal electrocardiogram (with no QT prolongation) and normal basic laboratory tests. In the absence of other causes, clarithromycin was implicated as the likely cause of the patient’s dizziness. This case illustrates a rare but important adverse effect of clarithromycin in an older patient, and highlights the need to recognize drug-induced dizziness, differentiate it from other etiologies, and manage it appropriately to ensure both effective treatment of the infection and patient safety.