TITLE:
Hypercalcemia in a Seminoma
AUTHORS:
Alexander Kreze, Kristina Klemperová, Quynh Vu, Zuzana Špůrková, Lenka Balážová, Oliver Kuchař, Jason Joachim Kolesár
KEYWORDS:
Paraneoplasic Hypercalcemia, Seminoma, 1, 25-dihydroxyvitamin D
JOURNAL NAME:
Open Access Library Journal,
Vol.12 No.9,
September
9,
2025
ABSTRACT: Background: The association of seminoma with malignant hypercalcemia is extremely rare. Case findings: We present a 32-year-old male with hypercalcemia. Subsequently, a metastatic seminoma was discovered according to computed tomography and biopsy testing. Elevated 1,25-dihydroxyvitamin D levels were identified as the cause of hypercalcemia. Conclusion: Hypercalcemia is a rare but possible scenario in seminoma and therefore it is important to consider this uncommon cause in the differential diagnosis.