TITLE:
Epidemiological and Clinical Aspects of Ischemic Heart Disease in HIV/AIDS Immunodepression in Infectious Diseases Department of the Chu Point “G”
AUTHORS:
Sidibé Samba, Coulibaly Souleymane, Diarra Aminata, Konaté Massama, Sako Mariam, Mariko Souleymane, Camara Youssouf, Menta Ichaka
KEYWORDS:
Myocardial Ischemia, HIV/AIDS, Bamako
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.15 No.9,
September
1,
2025
ABSTRACT: The cardiovascular prognosis of patients infected with the human immunodeficiency virus will become an increasingly important concern for physicians treating this infection in the coming years. Ischemic heart disease results from insufficient oxygenation of the myocardium due to narrowing or occlusion of one or more coronary arteries. Objective: This study aimed to describe the epidemiological and clinical aspects of ischemic heart disease in immunocompromised HIV patients hospitalized in a Infectious and Tropical Diseases Department of the Point “G” University Hospital, Bamako, Mali. Materials and Methods: This was a descriptive, cross-sectional study conducted from January 2019 to September 2019 on the records of HIV/AIDS patients with ischemic heart disease. Ischemic heart disease was diagnosed clinically, electrically, and by echocardiography. Result: The study involved 13 cases of ischemic heart disease in 331 hospitalized patients, representing a hospital prevalence of 3.9%. The sex ratio was 0.86%. The most affected age group was [50 - 59 years]. HIV1 infection represented 84.5% of cases. Cardiovascular risk factors found outside of HIV infection were dominated by hypertension 69.2% followed by dyslipidemia and smoking with 58.9% and 38.5% respectively. The left ventricular ejection fraction was less than 50% in the majority of cases. Complications were mainly dominated by ischemic stroke and anemia with the same percentage, i.e. 46.12%. We recorded 5 deaths with a case fatality rate of 38.5%. The outcome was favorable in 30.8% of patients with stable heart failure, an intermediate ejection fraction and sequelae such as hemiplegia or dysarthria. Conclusion: Ischemic heart disease in HIV-infected individuals is multifactorial in origin and carries a poor prognosis.